Dengue in children: clinical and epidemiological characteristics, Manaus, State of Amazonas, 2006 and 2007

Dengue in children: clinical and epidemiological characteristics, Manaus, State of Amazonas, 2006 and 2007
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DOI:
10.1590/s0037-86822009000100005
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发表时间:
2009-02-01
影响因子:
2
通讯作者:
Tauil, Pedro Luiz
Tauil, Pedro Luiz
中科院分区:
医学4区
文献类型:
--
作者:
Rocha, Lúcia Alves da;Tauil, Pedro Luiz

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这项研究介绍了2006年和2007年在马瑙斯,AM感染登革热的儿童的临床和流行病学方面。本研究的目的是介绍2006年和2007年亚马孙州马瑙斯受登革热影响的儿童的临床和流行病学特征。2006年对482例经实验室检测确诊的登革热病例进行了分析(15岁以下儿童占46.9%),2007年对1 538例病例进行了分析(15岁以下儿童占57.7%)。数据来自马瑙斯的国家法定传染病系统(Sistema Nacional de Agravos de Notificacao;希南)。分析的变量包括:年龄、性别、受试者居住的地区、症状开始的月份、疾病的血清型和临床形式。2006年至2007年期间,15岁以下儿童的病例比例和严重形式的比例在统计上显著增加。虽然2007年出血性疾病的发生率几乎增加了三倍,但死亡率较低。2006年确定的血清型为DEN-3,2007年确定的血清型为DEN-1、DEN-2和DEN-3。2007年,全年每个月都有病例记录。
This study presents the clinical and epidemiological aspects of children affected with dengue, in Manaus, AM, in 2006 and 2007. There were 482 The aim of this study was to present the clinical and epidemiological characteristics of children affected by dengue, in Manaus, State of Amazonas, in 2006 and 2007. Analysis was conducted on 482 dengue cases with confirmation from laboratory tests, in 2006 (46.9% in children under 15 years of age), and 1,538 cases in 2007 (57.7% in children under 15 years of age). The data were obtained from the National System for Notifiable Diseases (Sistema Nacional de Agravos de Notificacao; SINAN) in Manaus. The variables analyzed were: age, gender, district where subject lived, month when symptoms started, serotypes and clinical form of the disease. Statistically significant increases in the proportion of cases in children under 15 years of age and in the proportion of severe forms were found between 2006 and 2007. Although the hemorrhagic form was almost three times more frequent in 2007, the mortality rate was lower. The serotypes identified were DEN-3 in 2006 and DEN-1, DEN-2 and DEN-3 in 2007. In 2007, cases were recorded in every month of the year.