Diffusion tensor imaging and tractography of Rasmussen encephalitis
Diffusion tensor imaging and tractography of Rasmussen encephalitis
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DOI：
10.1007/s00247-009-1261-2
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发表时间：
2009-07-01
影响因子：
2.3
通讯作者：
Filippi, Christopher G.
中科院分区：
文献类型：
--
作者：
Cauley, Keith A.;Burbank, Heather N.;Filippi, Christopher G.
一个5岁的女孩表现为顽固性癫痫发作和脑电图非局灶性大脑半球减慢。血液、尿液和CSF实验室检查值均正常。脑部磁共振成像显示整个左半球弥漫性容量损失。临床和影像学表现与拉斯穆森脑炎的诊断一致。扩散张量成像显示受影响（左）半球的ADC值增加，各向异性分数（FA）降低。纤维束成像数据显示，相对于对侧半球或正常年龄匹配的对照组，受累半球的线条数量减少，FA阈值较高时线条较少。扩散张量成像提供了一种辅助的磁共振成像方式在诊断和监测这种罕见的情况。
A 5-year-old girl presented with intractable seizures and nonfocal hemispheric slowing on EEG. Blood, urine, and CSF laboratory values were all normal. MR imaging of the brain demonstrated diffuse volume loss of the entire left hemisphere. Clinical and imaging findings were consistent with the diagnosis of Rasmussen encephalitis. Diffusion tensor imaging demonstrated increased ADC values and decreased fractional anisotropy (FA) of the affected (left) hemisphere. Tractography data showed decreased numbers of lines drawn in the affected hemisphere, with fewer lines drawn at higher FA thresholds, relative to the contralateral hemisphere, or to normal age-matched controls. Diffusion tensor imaging offers an adjunct MR imaging modality in diagnosis and monitoring of this rare condition.