Live Birth in Woman With Premature Ovarian Insufficiency Receiving Ovarian Administration of Platelet-Rich Plasma (PRP) in Combination With Gonadotropin: A Case Report

Live Birth in Woman With Premature Ovarian Insufficiency Receiving Ovarian Administration of Platelet-Rich Plasma (PRP) in Combination With Gonadotropin: A Case Report
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DOI:
10.3389/fendo.2020.00050
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发表时间:
2020-02-19
影响因子:
5.2
通讯作者:
Dorjee, Sonam
Dorjee, Sonam
中科院分区:
医学2区
文献类型:
--
作者:
Hsu, Chao-Chin;Hsu, Leonard;Dorjee, Sonam

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卵巢早衰(POI)女性的受孕率仍然极低。为了成功怀孕,这些女性中的大多数必须通过体外受精治疗获得捐赠的卵母细胞。富含血小板血浆(PRP)的卵巢给药最近已被应用于增强卵巢反应较差的女性的排卵功能。然而,尚未有 POI 患者活产的报道。在这项研究中,我们介绍了一名患有 POI 的 37 岁女性,她有继发性闭经 6 个月。该卵巢功能减退女性的临床表现和评估是血清 AMH 水平检测不到(
The conception rates among women with premature ovarian insufficiency (POI) remain extremely low. To achieve a successful pregnancy, most of these women have to receive donor oocytes through IVF treatment. Ovarian administration of platelet-rich plasma (PRP) has been recently applied to enhance the ovulatory function in women with poor ovarian response. However, no live birth has been reported for this application in patients with POI. In this study, we present a 37-year-old woman with POI who had secondary amenorrhea for 6 months. The clinical manifestations and evaluation of this women with a diminished ovarian function were an undetectable serum level of AMH (