Detection of Mycoplasma ovipneumoniae in Pasteurella-vaccinated sheep flocks with respiratory disease in England
Detection of Mycoplasma ovipneumoniae in Pasteurella-vaccinated sheep flocks with respiratory disease in England
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DOI：
10.1136/vr.153.22.687
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发表时间：
2003-11-29
影响因子：
2.2
通讯作者：
Nicholas, RAJ
中科院分区：
文献类型：
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作者：
McAuliffe, L;Hatchell, FM;Nicholas, RAJ
在欧洲大陆，绵羊和山羊患有由支原体引起的多种严重疾病，特别是传染性无乳乳症和胸膜肺炎，由于牛奶产量、发病率和偶尔的死亡率下降，这些疾病导致重大的经济损失(Nicholas 2002)。相比之下，在英国，只有两种支原体被证明会导致小型反刍动物患病。它们是结膜支原体，它引起严重但自限性的角结膜炎(Baker等人2001年)，以及羊肺炎支原体，非进行性(非典型)肺炎的原因(Gilmour等人1979年)。在英国，很难衡量由肺炎支原体引起的肺炎的重要性，因为很少有实验室对这种支原体进行常规监测。然而，有一些迹象表明，它可能在越来越多的绵羊呼吸道疾病暴发中发挥重要作用。此外，溶血曼氏杆菌被认为是绵羊的主要致病细菌，一般情况下，一旦分离出来，就很难进行进一步的诊断。这份简短的信函描述了在接种了巴氏杆菌疫苗的患有呼吸道疾病的英国绵羊和山羊群中检测到绵羊肺炎支原体的情况。在2002年期间，对一些肺炎羊群中的绵羊和山羊进行了支原体检查，其中许多羊群中有持续咳嗽的母羊。尽管接种了梭状芽胞杆菌/巴氏杆菌联合疫苗(Heptavac-P Plus；INTERVET)，但选定的鸡群仍有呼吸道疾病的迹象。为了进行比较，在临床健康的相同大小和管理类型的羊群中也检查了较少数量的羔羊(表1)。此外,
SHEEP and goats suffer from a number of serious diseases caused by Mycoplasma species in mainland Europe, in par-ticular contagious agalactia and pleuropneumonias, which lead to significant economic losses as a result of decreases in milk production, morbidity and, occasionally, mortality (Nicholas 2002). In contrast, only two Mycoplasma species have been shown to cause disease in small ruminants in Britain. They are Mycoplasma conjunctivae, which causes a serious but self-limiting keratoconjunctivitis (Baker and oth-ers 2001), and Mycoplasma ovipneumoniae, the cause of a non-progressive (atypical) pneumonia (Gilmour and others 1979). It is difficult to gauge the importance of pneumonias caused by M ovipneumoniae in Britain because few laboratories routinely monitor for this mycoplasma. However, there are some indications that it may be significant in a growing number of outbreaks of respiratory disease in sheep. Further-more, Mannheimia haemolytica is considered to be the major pathogenic bacteriumin sheep and, generally, little further diagnosis is carried out once it has been isolated. This short communication describes the detection of M ovipneumoniae in English sheep and goat flocks with respiratory disease, which had been vaccinated with Pasteurella. During 2002, sheep and goats from a number of pneu-monic flocks, many containing ewes with persistent coughing, were examined for the presence of mycoplasmas. The flocks selected had signs of respiratory disease despite vaccination with a combined clostridial/Pasteurella vaccine (Heptavac-P Plus; Intervet). For comparison, a smaller num-ber of lambs in clinically healthy flocks of the same size and management type were also examined (Table 1). In addition,