Five comorbidities reflected the health status in patients with chronic obstructive pulmonary disease: the newly developed COMCOLD index
Five comorbidities reflected the health status in patients with chronic obstructive pulmonary disease: the newly developed COMCOLD index
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DOI：
10.1016/j.jclinepi.2014.03.005
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发表时间：
2014-08-01
影响因子：
7.2
通讯作者：
Puhan, Milo A.
中科院分区：
文献类型：
--
作者：
Frei, Anja;Muggensturm, Patrick;Puhan, Milo A.
目的：本研究旨在确定对慢性阻塞性肺病 (COPD) 患者报告的健康状况影响最大的合并症，并制定反映其综合影响的合并症指数。 研究设计和背景：我们在该横断面研究中纳入了来自慢性阻塞性肺病国际合作项目：恶化风险指数队列 (ICE COLD ERIC) 的 408 名瑞士和荷兰初级保健 COPD 患者分析。主要结果是感觉温度计，一种患者报告的健康状况仪器。我们使用针对 FEV1 调整的多元线性回归评估了五个队列评估时间中合并症的影响，保留合并症与 P 的关联
Objective: This study aimed to identify those comorbidities with greatest impact on patient-reported health status in patients with chronic obstructive pulmonary disease (COPD) and to develop a comorbidity index that reflects their combined impact.Study Design and Setting: We included 408 Swiss and Dutch primary care patients with COPD from the International Collaborative Effort on Chronic Obstructive Lung Disease: Exacerbation Risk Index Cohorts (ICE COLD ERIC) in this cross-sectional analysis. Primary outcome was the Feeling Thermometer, a patient-reported health status instrument. We assessed the impact of comorbidities at five cohort assessment times using multiple linear regression adjusted for FEV1, retaining comorbidities with associations P