Fragile X syndrome with anxiety disorder and exceptional verbal intelligence
Fragile X syndrome with anxiety disorder and exceptional verbal intelligence
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DOI：
10.1002/ajmg.a.32118
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发表时间：
2008-02-01
影响因子：
2
通讯作者：
Hagerman, Randi J.
中科院分区：
文献类型：
--
作者：
Angkustsiri, Kathleen;Wirojanan, Juthamas;Hagerman, Randi J.
脆性X综合征(FXS)通常以智力低下为特征。然而，FXS也与严重的情感和精神问题有关，包括焦虑、抑郁、注意力困难和在智商正常的情况下学习障碍。这份报告描述了一位独特的具有FXS全突变的女性，她具有高于平均水平的特殊智力特征，并有因焦虑和学习障碍而造成的严重障碍。患有FXS的女性主要表现为学习和情绪问题，临床医生应该考虑对这些女性进行FXS，而不管她们的智商如何。(C)2008年Wiley-Liss，Inc.
Fragile X syndrome (FXS) is often characterized by mental retardation. However, FXS is also associated with significant emotional and psychiatric problems, including anxiety, depression, attention difficulties, and learning disabilities in the presence of a normal IQ. This report describes a unique woman with the full mutation of FXS who has an exceptional profile of above-average intelligence combined with significant impairments due to anxiety and learning disability. Women with FXS can present primarily with learning and emotional problems, and clinicians should consider FXS in these women regardless of their IQ. (C) 2008 Wiley-Liss, Inc.