MOLECULAR EPIDEMIOLOGY OF MULTIRESISTANT STAPHYLOCOCCUS-EPIDERMIDIS
MOLECULAR EPIDEMIOLOGY OF MULTIRESISTANT STAPHYLOCOCCUS-EPIDERMIDIS
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DOI：
10.1093/jac/21.suppl_c.133
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发表时间：
1988-04-01
影响因子：
5.2
通讯作者：
ARCHER, GL
中科院分区：
文献类型：
--
作者：
ARCHER, GL
分子流行病学对医院内多重耐药凝固酶阴性葡萄球菌的抗菌素耐药基因提供了一些线索。首先，它表明患者和照顾他们的医院工作人员体内的这些生物体中保存着巨大的耐药基因库。反过来，医院特定部门内抗菌药物的广泛使用可能为这些基因的进化和扩增提供了选择压力。其次，间接证据表明表皮葡萄球菌本身可能是转移到表皮葡萄球菌的抗菌素耐药基因的储存库。金黄色葡萄球菌。
Molecular epidemiology has provided several dues about the antimicrobial resistance genes of nosocomial, multiresistant coagulase-negative staphylococci. First, it has shown that a huge reservoir of resistance genes is maintained in these organisms on the bodies of both patients and the hospital personnel who care for them. In turn, extensive use of antimicrobial agents within specific sectors of the hospital probably provides selection pressure for the evolution and amplification of these genes. Secondly, indirect evidence suggests thatStaphylococcus epidermidismay itself serve as a reservoir for antimicrobial resistance genes that are transferred toS. aureus.