Epidemiology of viral hepatitis among Iranian population--a viral marker study.

Epidemiology of viral hepatitis among Iranian population--a viral marker study.
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伊朗人群病毒性肝炎的流行病学——病毒标记研究。

DOI:
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发表时间:
1980
期刊:
Annals of the Academy of Medicine, Singapore
影响因子:
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通讯作者:
K. Noori
K. Noori
中科院分区:
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文献类型:
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作者:
H. Farzadegan;M. Shamszad;K. Noori

文献摘要

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我们的研究表明,伊朗病毒性肝炎的发病率比西方国家更常见。虽然该区域甲型肝炎的发病率没有得到彻底调查,但我们关于该疾病的第一份报告显示,30岁以上的成年人几乎完全免疫。我国无偿献血者HBsAg阳性率为3.5%。如果假设全国的发病率也是3.5%,那么在3500万伊朗人中可能有100万HBsAg携带者。这些带菌者是伊朗的一个主要健康问题。该区域其他国家的HBsAg发病率很可能也很高。因此,强烈建议采取控制和预防措施,如对捐献的血液和血液制品进行第三代乙肝检测。所有HBsAg阳性献血者都应接受面谈,并告知其血液中含有传染性病原体,在出血时必须仔细考虑这一点。其他高风险人群,如血液透析患者和工作人员以及血友病患者也应该作为乙肝疫苗接种的可能候选人进行调查。
Our studies revealed that the incidence of viral hepatitis in Iran is more common than in the western countries. Although the incidence of hepatitis type A in the region is not thoroughly investigated, our first report on this disease in our region reveals an almost complete immunity among adults after 30 years of age. The incidence of HBsAg among our voluntary blood donors is 3.5%. If it is assumed that the incidence rate in the whole country is also 3.5%, then it is possible that there are one million HBsAg carriers among 35 million Iranians. These carriers constitute a major health problem in Iran. There is a good possibility that the HBsAg incidence rate in the other countries of the region is similarly high. Therefore it is highly recommended that control and preventive measures such as third generation HB teting of donated blood and blood products become mandatory. All HBsAg positive donors should be interviewed and informed that their blood contains an infectious agent and this must be carefully considered at the times of bleeding. Other high risk groups such as haemodialysis patients and staff and haemophiliacs also should be investigated as possible candidates for HB vaccination.