Individual differences in pain responses.
Individual differences in pain responses.
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DOI：
10.1007/s11926-005-0018-7
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发表时间：
2005-10-01
影响因子：
5
通讯作者：
Fillingim, Roger B
中科院分区：
文献类型：
--
作者：
Fillingim, Roger B
疼痛体验的特点是个体间的巨大差异。事实上，相同的有害刺激会在个体之间产生截然不同的疼痛反应。从历史上看，科学家们认为这种可变性令人讨厌；然而，大量数据表明，这些个体差异可能提供有价值的信息，可用于加强疼痛的临床管理。本文讨论了导致疼痛感知个体差异的几个因素，包括人口统计学（即性别、年龄和种族）、遗传和社会心理变量。这些因素是在疼痛的生物心理社会模型的背景下讨论的，该模型假设疼痛感知受到生物、社会心理和社会文化因素之间的相互作用的影响。最后，讨论了个体疼痛差异的临床和科学意义。
The experience of pain is characterized by tremendous inter-individual variability. Indeed, an identical noxious stimulus can produce vastly different pain responses across individuals. Historically, scientists have regarded this variability as a nuisance; however, substantial data suggest that these individual differences may provide valuable information that can be used to enhance clinical management of pain. This paper discusses several factors that contribute to individual differences in pain perception, including demographic (ie, sex, age, and ethnicity), genetic, and psychosocial variables. These factors are discussed in the context of the biopsychosocial model of pain, which posits that pain perception is influenced by interactions among biologic, psychosocial, and sociocultural factors. Finally, the clinical and scientific implications of individual differences in pain are discussed.