Public Health Rationale for Rapid Nucleic Acid or p24 Antigen Tests for HIV
Public Health Rationale for Rapid Nucleic Acid or p24 Antigen Tests for HIV
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DOI：
10.1086/650393
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发表时间：
2010-04-15
影响因子：
6.4
通讯作者：
Golden, Matthew
中科院分区：
文献类型：
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作者：
Pilcher, Christopher D.;Christopoulos, Katerina A.;Golden, Matthew
能够检测人类免疫缺陷病毒 (HIV) 抗原或核酸的快速诊断测试代表了合并 HIV 测试的两项关键进步的可能性：快速测试和急性 HIV 感染检测。在本文中，我们回顾了快速艾滋病毒检测和急性艾滋病毒检测的公共卫生目标，并探讨了直接检测艾滋病毒抗原或核酸的快速检测如何改变临床和公共卫生筛查环境中当前艾滋病毒病例识别的方法。我们讨论了特定类型的艾滋病毒筛查计划和环境，其中直接病毒快速检测将提供重要优势。最后，我们建议运筹学中必须实现的优先事项，以便为未来在艾滋病毒检测市场中引入直接快速病毒检测技术铺平道路。
Rapid diagnostic tests that might be capable of detecting human immunodeficiency virus (HIV) antigens or nucleic acids represent the possibility of merging 2 key advancements in HIV testing: rapid testing and detection of acute HIV infection. In this article, we review the public health goals of rapid HIV testing and acute HIV testing and explore how rapid tests to directly detect HIV antigens or nucleic acids might alter current approaches to HIV case identification in clinical and public health screening settings. We discuss the specific types of HIV screening programs and settings in which direct viral rapid testing would offer an important advantage. Finally, we suggest priorities in operations research that must be achieved to pave the way for the future introduction of direct rapid viral testing technologies in the HIV testing marketplace.