Enhancing Surface Plasmon Detection Using Ultrasmall Nanoslits and a Multispectral Integration Method
Enhancing Surface Plasmon Detection Using Ultrasmall Nanoslits and a Multispectral Integration Method
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DOI：
10.1002/smll.201000598
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发表时间：
2010-09-06
期刊：
影响因子：
13.3
通讯作者：
Wei, Pei-Kuen
中科院分区：
文献类型：
--
作者：
Lee, Kuang-Li;Wei, Pei-Kuen
提出了一种提高金纳米结构检测限的多光谱积分方法。该方法考虑了局域表面等离子体、布洛赫波表面等离子体和伍德异常引起的所有共振。通过将波长变化与这些共振的强度变化结合起来，检测分辨率比常用的波长或强度方法提高了约六倍。对不同纳米结构的进一步研究表明，检测灵敏度随着孔径尺寸的减小而增加。 40 nm 纳米狭缝的检测限相对于 300 nm 纳米狭缝提高了约 7 倍。对于亚100 nm孔径，由于其非截止传输，纳米狭缝的检测分辨率优于纳米孔。通过抗原抗体相互作用实验验证了多光谱积分方法在生物传感中的优势。
A multispectral integration method to increase the detection limit of gold nanostructures is presented. This method considers all the resonances due to localized surface plasmons, Bloch wave surface plasmons, and Wood's anomalies. By integrating the wavelength shifts together with intensity changes over these resonances, the detection resolution is increased to about six times larger than that of commonly used wavelength or intensity methods. Further studies with different nanostructures show the detection sensitivity is increased with the decrease of aperture size. The detection limit for 40-nm nanoslits is improved by about seven times relative to that for 300-nm nanoslits. For sub-100-nm apertures, the detection resolution for nanoslits is better than that for nanoholes due to its non-cutoff transmission. The advantage of using the multispectral integration method in biosensing is verified by antigen-antibody interaction experiments.