Characterization of Tn2411 and Tn2410, two transposons derived from R-plasmid R1767 and related to Tn2603 and Tn21

Characterization of Tn2411 and Tn2410, two transposons derived from R-plasmid R1767 and related to Tn2603 and Tn21
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Tn2411 和 Tn2410(源自 R 质粒 R1767 且与 Tn2603 和 Tn21 相关的两个转座子)的表征

DOI:
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发表时间:
1983
影响因子:
3.2
通讯作者:
B. Wiedemann
B. Wiedemann
中科院分区:
生物学3区
文献类型:
--
作者:
J. Kratz;F. Schmidt;B. Wiedemann

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Two transposable elements, Tn2410 and Tn2411, were isolated from Salmonella typhimurium R-factor R1767. They have sizes of 18.5 and 18.0 kilobases, respectively. Tn2411 mediates resistance to streptomycin, sulfonamides, and mercury. In Tn2410, the streptomycin resistance gene was replaced by a gene coding for the production of the beta-lactamase OXA-2, which is responsible for ampicillin resistance. Physical and functional maps of both transposons were compared with those of Tn21, Tn4, and Tn2603. From these data it appeared that Tn21 could be an ancestral transposon from which Tn2411, Tn2410, Tn2603, and Tn4 were evolved by the addition or deletion of small DNA segments.