Enhancement of cerulenin production by a natural zeolite, an ammonium ion-trapping agent.
Enhancement of cerulenin production by a natural zeolite, an ammonium ion-trapping agent.
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通过天然沸石（一种铵离子捕获剂）增强浅蓝素的产生。
DOI：
10.7164/antibiotics.35.1184
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
S. Ōmura
中科院分区：
文献类型：
--
作者：
R. Masuma;Y. Tanaka;S. Ōmura
添加一种天然沸石，一种已知的铵离子捕获剂，复杂的介质中，导致在几倍的增加浅蓝菌素生产由Cephalosporium caerulens。沸石的加入使培养基中铵离子浓度降低，菌丝生长量略有增加，pH值保持不变。少量碳酸氢铵抑制浅蓝菌素的生产，而不影响菌丝生长和pH值。因此，推测沸石通过解除C.天蓝色的。
Addition of a natural zeolite, a known ammonium ion-trapping agent, to a complex medium resulted in a several fold increase in cerulenin production by Cephalosporium caerulens. In the presence of zeolite, ammonium ion in the medium decreased, while mycelial growth increased to a small extent, and pH values remained constant. Small amounts of ammonium bicarbonate inhibited cerulenin production without affecting mycelial growth and pH values. It is thus assumed that zeolite stimulated cerulenin production by releasing the biosynthesis from the suppression by ammonium ions in C. caerulens.