Rotation between markers of systemic vascular inflammation and smoking in women

Rotation between markers of systemic vascular inflammation and smoking in women
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DOI:
10.1016/s0002-9149(02)02284-1
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发表时间:
2002-05-01
影响因子:
2.8
通讯作者:
Ridker, PM
Ridker, PM
中科院分区:
医学3区
文献类型:
--
作者:
Bermudez, EA;Rifai, N;Ridker, PM

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我们对参加女性健康研究的表面健康的女性进行了分析,以确定基线高敏 C 反应蛋白、白细胞介素 6、可溶性细胞间粘附分子 1 型、P-选择素和 E-选择素与吸烟状况之间的关系。我们发现血管炎症标志物的循环水平与女性吸烟状况独立相关,这表明吸烟可能至少部分通过血管炎症促进动脉粥样硬化血栓形成。
We conducted an analysis among apparently healthy women enrolled in the Women's Health Study, to determine the relation between baseline high-sensitivity C-reactive protein, interleukin-6, soluble intercellular adhesion molecule type 1, P-selectin, and E-selectin with smoking status. We found that circulating levels of vascular inflammatory markers are independently related to smoking status in women, suggesting that smoking may promote atherothrombosis, at least in part, through vascular inflammation.