Procalcitonin is associated with postnatal respiratory condition severity in preterm neonate
Procalcitonin is associated with postnatal respiratory condition severity in preterm neonate
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DOI：
10.1002/ppul.25846
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发表时间：
2022-01
影响因子：
3.1
通讯作者：
M. Iwai;H. Yoshimatsu;T. Naramura;H. Imamura;Tomomi Nakamura;Rieko Sakamoto;Takeshi Inoue;Kenichi Tanaka;Shirou Matsumoto;Kimitoshi Nakamura;H. Mitsubuchi
中科院分区：
文献类型：
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作者：
M. Iwai;H. Yoshimatsu;T. Naramura;H. Imamura;Tomomi Nakamura;Rieko Sakamoto;Takeshi Inoue;Kenichi Tanaka;Shirou Matsumoto;Kimitoshi Nakamura;H. Mitsubuchi
出生后呼吸衰竭在早产儿中很常见，很难通过临床症状与早发性新生儿细菌感染区分。与C反应蛋白（CRP）类似，降钙素原（PCT）被用作细菌感染的标志物。近年来，有报道称出生后呼吸衰竭会导致血清PCT水平升高。然而，关于生物学炎症标志物（如PCT和CRP）与出生后呼吸道疾病严重程度之间的关系的信息不足。
Postnatal respiratory failure is common in preterm neonates and is difficult to distinguish from early‐onset neonatal bacterial infection by clinical symptoms. Similar to C‐reactive protein (CRP), procalcitonin (PCT) is used as a marker of bacterial infection. Recently, it has been reported that the serum PCT levels increase because of respiratory failure immediately after birth. However, there is insufficient information concerning the relationship between biological inflammation markers, such as PCT and CRP, and postnatal respiratory condition severity.