Slit-Robo: Neuronal guides signal in tumor angiogenesis

Slit-Robo: Neuronal guides signal in tumor angiogenesis
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DOI:
10.1016/s1535-6108(03)00166-1
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发表时间:
2003-07-01
期刊:
影响因子:
50.3
通讯作者:
Herlyn, M
Herlyn, M
中科院分区:
医学1区
文献类型:
--
作者:
Liu, ZJ;Herlyn, M

文献摘要

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Slit和Roundabout(Robo)在神经元和白细胞引导方面具有良好的特征。它们的调控作用现已扩展到控制肿瘤-内皮细胞通讯和介导肿瘤诱导的血管生成。
Slit and Roundabout (Robo) are well-characterized for neuron and leukocyte guidance. Their governing roles have now been expanded to control tumor-endothelial cell communication and mediate tumor-induced angiogenesis.