Distribution of causes of maternal mortality during delivery and post-partum: results of an African multicentre hospital-based study
Distribution of causes of maternal mortality during delivery and post-partum: results of an African multicentre hospital-based study
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DOI：
10.1016/j.ejogrb.2003.12.004
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发表时间：
2004-06-15
影响因子：
2.6
通讯作者：
Goyaux, N
中科院分区：
文献类型：
--
作者：
Thonneau, PF;Matsudai, T;Goyaux, N
目的：评估西非大城市参考医院产科的产妇死亡率，并说明并发症的分布情况和产妇死亡原因。研究设计：在三个非洲国家（贝宁，象牙海岸，塞内加尔）的12个参考产妇中进行前瞻性描述性研究。从产科和外科档案和入院登记册收集数据（入院时的临床表现、病史、并发症、手术类型、出院时妇女的生命状态）。非洲和欧洲工作人员对所有产妇死亡案例进行了系统审查。结果如下：在总共10 515名妇女中，有1 495名妇女出现重大产科并发症，其中难产或产程管理不当是主要原因。据报有85名产妇死亡，全球医院产妇死亡率为800/100 000。25/85例病例（29%）涉及高血压疾病，13/85例病例（15%）涉及产后出血。报告的严重脓毒症病例相对较少（14例），导致3例产妇死亡。结论：这一多中心研究的结果证实，非洲大城市参考医院产科的产妇死亡率很高，除难产外，高血压和产后出血也是产妇死亡的原因。(C)2003爱思唯尔爱尔兰有限公司保留所有权利。
Objective: To assess the maternal mortality ratio in maternity units of reference hospitals in large west African cities, and to describe the distribution of complications and causes of maternal deaths. Study design: Prospective descriptive study in twelve reference maternities located in three African countries (Benin, Ivory Coast, Senegal). Data (clinical findings at hospital entry, medical history, complications, type of surgery, vital status of the women at discharge) were collected from obstetrical and surgical files and from admission hospital registers. All cases of maternal deaths were systematically reviewed by African and European staff. Results: Of a total of 10,515 women, 1495 presented a major obstetric complication with dystocia or inappropriate management of the labour phase as the leading cause. Eighty-five maternal deaths were reported, giving a global hospital-based maternal mortality ratio of 800/100,000. Hypertensive disorders were involved in 25/85 cases (29%) and post-partum haemorrhage in 13/85 cases (15%). Relatively few cases (14) of major sepsis were reported, leading to three maternal deaths. Conclusion: The results of this multicentre study confirm the high rates of maternal mortality in maternity units of reference hospitals in large African cities, and in addition to dystocia the contribution of hypertensive disorders and post-partum haemorrhage to maternal deaths. (C) 2003 Elsevier Ireland Ltd. All rights reserved.