Stress resistance and environmental dependency of inbreeding depression in Drosophila melanogaster
Stress resistance and environmental dependency of inbreeding depression in Drosophila melanogaster
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DOI：
10.1046/j.1523-1739.2000.99206.x
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发表时间：
2000-08-01
影响因子：
6.3
通讯作者：
Hoffmann, AA
中科院分区：
文献类型：
--
作者：
Dahlgaard, J;Hoffmann, AA
近交和环境压力都可能对适应性产生不利影响，从而影响濒危物种的保护。两个重要的问题是，压力和近交的影响是独立的还是协同的，以及近交的影响是普遍的，而不是特定的压力。我们发现近亲繁殖降低了成年黑腹果蝇对丙酮和干燥的抗性，而对低敲热应激的抗性不受影响。然而，在高温胁迫下，近亲繁殖的果蝇的生产力比近亲繁殖的果蝇下降的比例更大。用系均值进行相关分析表明，近交系和远交系的所有抗性性状均不相关。因此，隐性有害等位基因似乎对抗逆性没有任何普遍的有害影响。因此，在特定环境内的近亲繁殖和抗性基因型的选择可能清除只对一种环境胁迫具有特异性的有害基因群体。
Both inbreeding and environmental stress can have adverse effects on fitness that affect the conservation of endangered species. Two important issues are whether stress and inbreeding effects are independent as opposed to synergistic, and whether inbreeding effects are general across stresses as opposed to stress-specific. We found that inbreeding reduced resistance to acetone and desiccation in adult Drosophila melanogaster, whereas resistance to knockdown heat stress was not affected. Inbred flies, however, experienced a greater proportional decrease in productivity than outbreds following heat stress. Correlations using line means indicated that all resistance traits were uncorrelated in the inbred as well as in the outbred flies. Recessive, deleterious alleles therefore did not appear to have any general deleterious effects on stress resistance. Inbreeding within a specific environment and selection for resistant genotypes may therefore purge a population of deleterious genes specific to only one environmental stress.