CORRELATION BETWEEN RADIOLOGICAL AND PATHOLOGICAL DIAGNOSIS OF SILICOSIS - AN AUTOPSY POPULATION-BASED STUDY
CORRELATION BETWEEN RADIOLOGICAL AND PATHOLOGICAL DIAGNOSIS OF SILICOSIS - AN AUTOPSY POPULATION-BASED STUDY
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DOI：
10.1002/ajim.4700240408
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发表时间：
1993-10-01
影响因子：
3.5
通讯作者：
THOMAS, RG
中科院分区：
文献类型：
--
作者：
HNIZDO, E;MURRAY, J;THOMAS, RG
将557名金矿工人的大量圆形混浊物的放射学表现与实质性矽肺病的病理表现进行比较，这些矿工的放射学和病理检查之间平均间隔2.7年。三位读者阅读了x线片，ILO分类1/1或以上被定义为矽肺的阳性诊断。3种阅读器的灵敏度分别为0.393、0.371、0.236，特异度分别为0.987、0.965、0.978。随着尸检矽肺程度的增加，阅读器的敏感性提高，但有很大比例的中度和显著程度的矽肺未被放射诊断。通过使用0/1类作为暴露于高平均浓度可吸入二氧化硅粉尘的工人的截止点，可以提高放射试验的诊断敏感性。使用1/0或1/1分类作为暴露于低平均呼吸性硅尘的工人的阳性诊断的截止点，可以提高放射学的诊断特异性。(C) 1993 Wiley-Liss, Inc。
The radiological findings for the profusion of rounded opacities were compared to pathological findings for parenchymal silicosis in 557 gold miners who had, on average, 2.7 years between the radiological and pathological examination. Three readers read the radiographs, and ILO category 1/1 or more was defined as a positive diagnosis of silicosis. The sensitivity values were 0.393, 0.371, and 0.236, and the specificity values were 0.987, 0.965, and 0.978, for the three readers, respectively. The sensitivity of the readers improved with increasing degree of autopsy silicosis, but a large proportion of those with a moderate and marked degree of silicosis were not diagnosed radiologically. The diagnostic sensitivity of the radiological test could be improved by using category 0/1 as a cutoff point for workers exposed to a high average concentration of respirable silica dust. The diagnostic specificity of radiology could be improved by using category 1/0 or 1/1 as a cutoff point for a positive diagnosis for workers exposed to a low average concentration of respirable silica dust. (C) 1993 Wiley-Liss, Inc.