Intermittent Claudication: Surgical Significance
Intermittent Claudication: Surgical Significance
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间歇性跛行：手术意义
DOI：
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发表时间：
1974
期刊：
影响因子：
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通讯作者：
P. McNamara
中科院分区：
文献类型：
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作者：
C. Peabody;W. Kannel;P. McNamara
对162例间歇性跛行患者进行了平均8.3年的观察。这些病例均来自18年随访期间的人群队列。他们基本上未经治疗，直到休息疼痛和组织损失开始。只有四个进展到大截肢和三个脚趾损失。间歇性跛行和坏疽患者的个人资料显示，糖尿病和吸烟习惯以及高血压和高血脂症的患病率较高。冠心病、中风和充血性心力衰竭的合并症和后续发生率较高。在八年内，几乎一半的人发生了严重的心血管事件，20%的男性和30%的女性死亡。这种心血管发病率和死亡率以及间歇性跛行在无心血管疾病的一般人群中是可预测的。考虑进行旁路手术的患者，如果唯一的主诉是跛行，应仔细评估其心血管发病率。
A study was made of 162 persons with intermittent claudication who were observed for an average of 8.3 years. These were all the cases that evolved from a population cohort during 18 years of follow-up. They were essentially untreated until rest pain and tissue loss began. Only four progressed to major amputations and three to toe loss. A profile of the person developing intermittent claudication and gangrene in particular reveals a higher prevalence of diabetes and the cigarette habit, as well as hypertension and hypercholesteremia. The comorbidity and subsequent incidence of coronary disease, stroke, and congestive failure was high. Within eight years, almost half developed a major cardiovascular event and 20% of the men and 30% of the women were dead. This cardiovascular morbidity and mortality, as well as intermittent claudication, is predictable in the general population free of cardiovascular disease. Patients being considered for bypass surgery whose only complaint is claudication should be carefully evaluated for risk of cardiovascular morbidity.