Allele frequencies of 15 STRs in a representative sample of the Brazilian population.
Allele frequencies of 15 STRs in a representative sample of the Brazilian population.
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巴西人口代表性样本中 15 个 STR 的等位基因频率。
DOI：
10.1016/j.fsigen.2009.05.006
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
C. D. da Silva
中科院分区：
文献类型：
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作者：
Lilian de Assis Poiares;Paulo de Sá Osorio;F. Spanhol;Sidnei César Coltre;R. Rodenbusch;L. Gusmão;Álvaro Largura;F. Sandrini;C. D. da Silva
15个短串联重复序列（STR）基因座的等位基因频率从样本的12,030人进行亲子鉴定。该样本包括巴西所有州的个人，根据目前的国家划分分为五个地区（北部，东北部，中西部，东南部和南部）。多态性最高的位点是D2 S1338和D18 S51。所有分析的基因座都符合Hardy-Weinberg平衡预期。15个STR基因座的综合鉴别力和综合排除力分别为0.9999999999990和0.99999992。来自不同的巴西大区域的人口之间的比较分析，以及巴西和其他有关人口之间的比较分析。
Allele frequencies for 15 short tandem repeat (STR) loci were obtained from a sample of 12,030 individuals undergoing paternity testing. This sample includes individuals from all States in Brazil, combined according to the current country division into five regions (North, Northeast, Central West, Southeast, and South). The most polymorphic loci were D2S1338 and D18S51. All the analysed loci meet Hardy–Weinberg equilibrium expectations. Combined power of discrimination and combined power of exclusion for the 15 tested STR loci were 0.999999999999990 and 0.9999992, respectively. Comparative analysis between populations from different Brazilian macroregions as well as between Brazil and other relevant populations are presented.