Dakin's solution: is there a place for it in the 21st century?
Dakin's solution: is there a place for it in the 21st century?
复制标题
DOI：
10.1111/iwj.12728
复制
发表时间：
2017-12-01
影响因子：
3.1
通讯作者：
Neves, Jose
中科院分区：
文献类型：
--
作者：
Duarte, Bruno;Cabete, Joana;Neves, Jose
达金溶液（DS）是一种历史悠久的防腐剂，仍然是伤口护理设备的一部分。尽管它有细胞毒性，但有人质疑它在当今时代的使用。我们报告的情况下，52岁的糖尿病妇女谁是承认败血症，因为严重感染糖尿病足。紧急手术引流和清创留下了一个9 x 9 cm深的复杂感染伤口，累及骨和肌腱。局部负压治疗不成功。通过留在伤口敷料中的管定期滴注DS。使用该策略观察到显著改善，因为6周后伤口床更清洁且完全颗粒化。未观察到不良反应。这个案例揭穿了局部防腐剂必然会损害伤口愈合的神话。DS仍然可以被认为是难以治疗、复杂和严重感染伤口的一种选择。
Dakin's solution (DS) is a time-honoured antiseptic that still remains part of the wound care armamentarium. In spite of its cytotoxicity, some question its use in the current era. We report the case of a 52-year-old diabetic woman who was admitted for sepsis because of a severely infected diabetic foot. Urgent surgical drainage and debridement left a 9 x 9-cm deep, complex, infected wound with both bone and tendon involvement. Treatment with local negative pressure was unsuccessful. DS was regularly instilled through a tube left in the wound dressing. A marked improvement was observed with this strategy as the wound bed was much cleaner and fully granulated after 6 weeks. No adverse effects were noted. This case debunks the myth that topical antiseptics necessarily impair wound healing. DS can still be considered an option for difficult-to-treat, complex and heavily infected wounds.