Proton beam therapy interference with implanted cardiac pacemakers
Proton beam therapy interference with implanted cardiac pacemakers
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DOI：
10.1016/j.ijrobp.2008.01.062
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发表时间：
2008-11-01
影响因子：
7
通讯作者：
Tokuuye, Koichi
中科院分区：
文献类型：
--
作者：
Oshiro, Yoshiko;Sugahara, Shinji;Tokuuye, Koichi
目的：探讨质子束治疗（PBT）对植入式心脏起搏器function.Methods和Materials的影响：一个幻影的研究证实了PBT在心脏起搏器患者的安全性后，我们治疗了8例植入式心脏起搏器使用PBT的总肿瘤剂量为33-77戈瑞当量（GyE）的剂量分数为2.2-6.6 GyE。PBT会议的总次数为127次。尽管所有脉冲发生器均位于治疗野外，但4名患者的起搏电极导线仍处于辐射中。所有患者在治疗过程中均进行心电图监测，并在PBT前后常规检查起搏器。结果：体模研究显示中子散射油起搏器发生器无影响。在研究中，2例患者（2.4%）发生了3次心率变化。然而，这些患者在整个PBT course.Conclusions：PBT可以导致起搏器功能障碍，表现为脉搏率和脉冲模式的变化。因此。在PBT期间，应通过心电图监测心脏起搏器患者。(C)2008年爱思唯尔公司
Purpose: To investigate the effect of proton beam therapy (PBT) on implanted cardiac pacemaker function.Methods and Materials: After a phantom study confirmed the safety of PBT in patients with cardiac pacemakers, we treated 8 patients with implanted pacemakers using PBT to a total tumor dose of 33-77 gray equivalents (GyE) in dose fractions of 2.2-6.6 GyE. The combined total number of PBT sessions was 127. Although all pulse generators remained outside the treatment field, 4 patients had pacing leads in the radiation held. All patients were monitored by means of electrocardiogram during treatment, and pacemakers were routinely examined before and after PBT.Results: The phantom study showed no effect of neutron scatter oil pacemaker generators. In the study changes in heart rate occurred three times (2.4%) in 2 patients. However, these patients remained completely asymptomatic throughout the PBT course.Conclusions: PBT can result in pacemaker malfunctions that manifest as changes in pulse rate and pulse patterns. Therefore. patients with cardiac pacemakers should be monitored by means of electrocardiogram during PBT. (C) 2008 Elsevier Inc.