FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF THE CENTRAL AUDITORY PATHWAY FOLLOWING SPEECH AND PURE-TONE STIMULI
FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF THE CENTRAL AUDITORY PATHWAY FOLLOWING SPEECH AND PURE-TONE STIMULI
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DOI：
10.1288/00005537-199512000-00008
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发表时间：
1995-12-01
期刊：
影响因子：
2.6
通讯作者：
YETKIN, Z
中科院分区：
文献类型：
--
作者：
MILLEN, SJ;HAUGHTON, VM;YETKIN, Z
功能磁共振成像(FMRI)是一种新的无创脑功能成像技术。对人类中枢听觉通路的研究检测了8名正常听力志愿者对包括叙述性言语和纯音测听在内的听觉刺激的反应。fMRI显示的激活是建立在局部血流量增加和神经元增加的模型上的。活动。FMRI信号代表了大脑区域内毛细血管内脱氧血红蛋白浓度的变化，即在文本阅读和纯音调过程中，激活的大脑在颞上回被成像。文本和纯音呈现中的激活都不随听觉刺激的强度而变化，并在左侧颞叶引起主导反应。这些观察表明，功能磁共振成像能够将人类中枢听觉通路中的解剖和功能关系联系起来。
Functional magnetic resonance imaging (FMRI) is a new noninvasive technique for imaging cerebral function. Studies of the human central auditory pathway examined responses in eight normal hearing volunteers following auditory stimuli, including narrative speech and pure-tone audiometry.The activation demonstrated by FMRI is modeled on an increase in regional blood flow with increased neuronal. activity. The FMRI signals represent deoxyhemoglobin concentration changes in capillaries within the region of the brain that is activated Brain activation was imaged in the superior temporal gyrus during text reading and pure tones. Activation in both text and pure-tone presentation did not vary with the intensity of the auditory stimulus and elicited a dominant response in the left temporal lobe.These observations demonstrate the capability of FMRI to correlate anatomic and functional relationships in the human central auditory pathway.