Synthetic cannabinoids to avoid urine drug screens: Implications for contingency management and other treatments for drug dependence.

Synthetic cannabinoids to avoid urine drug screens: Implications for contingency management and other treatments for drug dependence.
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合成大麻素以避免尿液药物筛查:对药物依赖的应急管理和其他治疗的影响。

DOI:
10.1016/j.addbeh.2016.07.004
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发表时间:
2016
影响因子:
4.4
通讯作者:
Lejuez,CW
Lejuez,CW
中科院分区:
医学2区
文献类型:
--
作者:
Ninnemann,AndrewL;Lechner,WilliamV;Borges,Allison;Lejuez,CW

文献摘要

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应急管理(CM)是治疗药物依赖的有效方法。在CM中,奖励或代金券作为物质使用的替代品,促进持续的禁欲。然而,CM依赖于使用准确的生化验证方法,如尿液分析,以验证禁欲。合成大麻素(SC)对CM治疗构成风险,因为它们不容易通过普通尿液分析技术检测到。虽然性剥削构成风险,但关于物质依赖人群中目前性剥削使用率以及在使用性剥削治疗的人群中物质使用率和精神疾病率的信息有限。我们讨论了这些主题的新兴研究和CM治疗的潜在影响。研究结果表明,CM研究应测试和查询SC使用大麻和可卡因使用问题,以及在药物使用者的年轻人群中治疗。其他新的精神活性物质的药物治疗和药物尿分析的影响也进行了讨论。
Contingency management (CM) is an effective treatment for substance use dependence. Within CM, rewards or vouchers promote continued abstinence by acting as alternative reinforcers to substance use. However, CM relies on the use of accurate biochemical verification methods, such as urinalysis, to verify abstinence. Synthetic cannabinoids (SCs) pose a risk for CM treatment because they are not easily detected by common urinalysis techniques. Although SCs pose a risk, there is limited information regarding current rates of SC use within substance dependent populations as well as rates of substance use and psychiatric disorders among those who use SCs in treatment. We discuss emerging research on these topics and potential implications for CM treatments. Findings suggest CM researches should test for and query SC use among those being treated for cannabis and cocaine use problems as well as among younger populations of substance users. Implications of other novel psychoactive substances for drug treatment and drug urinalysis are also discussed.