Mandibular cuniculatum carcinoma: Apropos of 3 cases and literature review
Mandibular cuniculatum carcinoma: Apropos of 3 cases and literature review
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DOI：
10.1002/hed.21493
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发表时间：
2012-02-01
影响因子：
2.9
通讯作者：
Ruhin-Poncet, Blandine
中科院分区：
文献类型：
--
作者：
Pons, Yoann;Kerrary, Siham;Ruhin-Poncet, Blandine
背景 尖形癌是一种高度分化的鳞状细胞癌，与乳头状鳞状细胞癌和疣状癌具有相同的组织学特征。爪形癌多发生于足底，文献报道仅16例累及口腔的病例。方法。作者报道了 3 例下颌角癌病例。所有的病人都承受着极大的痛苦。由于细胞异型性很少，组织学诊断很困难。临床标准、骨质溶解以及同时存在多个骨内分化良好、角化过度的乳头状瘤病变且细胞异型性极少，这些都是诊断的标志。结果。单纯根治性手术治疗后未见局部复发的报道。结论。诊断常常被延误。尽管钩状癌局部表现出侵袭性，但淋巴结浸润和转移很少见。选择的治疗方法是手术切除游离切缘，术后预后良好。 (C) 2010 年 Wiley 期刊公司 Head Neck 34：291-295，2012 年
Background Cuniculatum carcinoma is a well-differentiated form of squamous cell carcinoma that shares histologic characteristics with papillary squamous cell carcinoma and verrucous carcinoma. Cuniculatum carcinoma usually occurs on the plantar region, and only 16 cases involving the oral cavity have been described in the literature.Methods. The authors have reported 3 cases of mandibular cuniculatum carcinoma. All of the patients were in a great deal of pain. Histologic diagnosis was difficult due to the presence of few cellular atypies. Clinical criteria, osseous lysis, and the coexistence of multiple intraosseous well-differentiated, hyperkeratotic papillomatous lesions with few cellular atypies sign the diagnosis.Results. No local recurrence has been reported after treatment with radical surgery alone.Conclusion. The diagnosis is often delayed. Although cuniculatum carcinoma displays aggressive behavior locally, lymph node infiltration and metastasis are rare. The therapy of choice is surgical removal with free margins, after which the prognosis is excellent. (C) 2010 Wiley Periodicals, Inc. Head Neck 34: 291-295, 2012