ANTIBACTERIAL ACTIVITY OF JULIFLORINE ISOLATED FROM PROSOPIS-JULIFLORA
ANTIBACTERIAL ACTIVITY OF JULIFLORINE ISOLATED FROM PROSOPIS-JULIFLORA
复制标题
DOI：
10.1055/s-2007-969153
复制
发表时间：
1986-08-01
期刊：
影响因子：
2.7
通讯作者：
QAZI, S
中科院分区：
文献类型：
--
作者：
AHMAD, A;KHAN, KA;QAZI, S
胡荽碱是从牧豆草中分离得到的一种生物碱，具有抗菌活性。在青霉素、链霉素、红霉素、磺胺甲恶唑、氨苄青霉素和四环素的可比浓度下，对6种革兰氏阳性菌和10种革兰氏阴性菌进行了体外活性测试。在革兰氏阳性菌中，发现juliflorine对化脓性链球菌、金黄色葡萄球菌、白喉棒状杆菌等有效。mitis、细叶弯角藻C.和枯草芽孢杆菌。粪链球菌被发现耐所有抗生素，除了氨苄西林和juliflorine。对沙门氏菌、志贺菌、变形杆菌、假单胞菌、克雷伯菌和大肠杆菌等菌无明显抑制作用。
Juliflorine, an alkaloid isolated from Prosopis juliflora is shown to possess antibacterial activity. This activity was tested in vitro against six Gram positive and ten Gram negative bacteria at comparable concentrations of penicillin, streptomycin, erythromycin, sulphamethoxazole, ampicillin and tetracycline. Among Gram positive bacteria juliflorine was found to be effective against Streptococcus pyogenes, Staphylococcus aureus, Corynebacterium diphtheriae var. mitis, C. hofmannii and Bacillus subtilis. Streptococcus faecalis was found resistant to all antibotics used except for ampicillin and juliflorine. No significant inhibitory effect of juliflorine was found against the species of Salmonella, Shigella, Proteus, Pseudomonas, Klebsiella and Escherichia coli.