Prevalence and associations of epiretinal membranes in an adult Japanese population: the Funagata study
Prevalence and associations of epiretinal membranes in an adult Japanese population: the Funagata study
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DOI：
10.1038/eye.2008.238
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发表时间：
2009-05-01
期刊：
影响因子：
3.9
通讯作者：
Wong, T. Y.
中科院分区：
文献类型：
--
作者：
Kawasaki, R.;Wang, J. J.;Wong, T. Y.
目的了解日本人群视网膜前膜（ERM）的患病率及其危险因素。2000年6月至2002年6月，Funagata研究调查了1758名35岁及以上的日本人（42%符合条件）。使用蓝山眼科研究（BMES）方案，共有1723名（98.0%）参与者有右眼无散瞳眼底照片来评估ERM的存在。在年龄标准化后，将本研究纳入的参与者的右眼ERM患病率与BMES和Beaver Dam Eye study （BDES）中参与者的右眼ERM患病率进行比较。在糖尿病视网膜病变和其他视网膜病变的眼睛中检测到的ERM被排除在相关性分析之外。采用多逻辑回归模型确定ERM存在的危险因素，并对年龄和性别进行调整。结果右眼ERM 84只，占5.44%。年龄标准化后，患病率（5.7%）在BMES（3.5%）和BDES（6.9%）报告的范围内。年龄较大（每10年性别调整比值比（OR）： 1.72, 95%可信区间（CI）： 1.40-2.11）和糖尿病（年龄-性别调整比值比：1.84,95% CI: 1.01-3.37）是仅有的两个与ERM相关的因素。结论：我们发现日本人的ERM患病率与以白人为主的人群相似。年龄增长和糖尿病是日本成年人群发生ERM的危险因素。眼科学（2009）23,1045-1051；doi: 10.1038 / eye.2008.238;2008年8月8日在线发布
Purpose To determine the prevalence and risk factors of epiretinal membranes (ERM) in a Japanese population.Patients and Methods The Funagata Study examined 1758 Japanese aged 35 years or older (42% of eligible) from June 2000 to June 2002. A total of 1723 (98.0%) participants had non-mydriatic fundus photographs of the right eye to grade the presence of ERM, using the Blue Mountains Eye Study (BMES) protocol. After age standardization, the prevalence of ERM in the right eyes of the participants included in this study was compared with that reported from right eyes of participants in the BMES and the Beaver Dam Eye Study (BDES). ERM detected in eyes with diabetic retinopathy and other retinal lesions were excluded from the analysis of associations. Multiple logistic regression models were used to determine risk factors for the presence of ERM, adjusting for age and gender.Results There were 84 right eyes with ERM, representing 5.44% of this sample. After age standardization, the prevalence rate (5.7%) was within the range reported in the BMES (3.5%) and the BDES (6.9%). Older age (gender-adjusted odds ratio (OR) per 10 years: 1.72, 95% confidence interval (CI): 1.40-2.11) and diabetes (age-gender-adjusted OR: 1.84, 95% CI: 1.01-3.37) were the only two factors associated with ERM.Conclusions We found a similar prevalence of ERM in the Japanese as in mainly white populations. Increasing age and diabetes were risk factors for ERM in this adult Japanese population. Eye (2009) 23, 1045-1051; doi:10.1038/eye.2008.238; published online 8 August 2008