Root extracellular traps versus neutrophil extracellular traps in host defence, a case of functional convergence?
Root extracellular traps versus neutrophil extracellular traps in host defence, a case of functional convergence?
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DOI：
10.1111/brv.12522
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发表时间：
2019-10-01
影响因子：
10
通讯作者：
Moore, John
中科院分区：
文献类型：
--
作者：
Driouich, Azeddine;Smith, Carine;Moore, John
根冠释放细胞，产生大量含有多糖、蛋白聚糖、细胞外DNA（exDNA）和多种抗微生物化合物的粘液。释放的细胞-称为边缘细胞或边缘样细胞-和粘液分泌物形成网络，被定义为根细胞外陷阱（RET）。可再生能源技术是根源免疫的重要角色。在动物中，吞噬细胞是循环中最丰富的白色血细胞，对免疫非常重要。这些细胞通过多种防御机制对抗病原体，包括释放含有exDNA的细胞外陷阱（exDNA trap，简称exDNA）。嗜中性粒细胞来源的陷阱在本文中缩写为NET。与吞噬细胞类似，植物根冠起源细胞积极地贡献于抵抗病原体的前线防御。因此，RET和NET分别是植物和动物免疫系统的组成部分，表现出相似的组成和功能特性。在这里，我们描述和讨论这些相似但不同的细胞外陷阱的形成，分子组成和功能相似性。
The root cap releases cells that produce massive amounts of mucilage containing polysaccharides, proteoglycans, extracellular DNA (exDNA) and a variety of antimicrobial compounds. The released cells - known as border cells or border-like cells - and mucilage secretions form networks that are defined as root extracellular traps (RETs). RETs are important players in root immunity. In animals, phagocytes are some of the most abundant white blood cells in circulation and are very important for immunity. These cells combat pathogens through multiple defence mechanisms, including the release of exDNA-containing extracellular traps (ETs). Traps of neutrophil origin are abbreviated herein as NETs. Similar to phagocytes, plant root cap-originating cells actively contribute to frontline defence against pathogens. RETs and NETs are thus components of the plant and animal immune systems, respectively, that exhibit similar compositional and functional properties. Herein, we describe and discuss the formation, molecular composition and functional similarities of these similar but different extracellular traps.