Carbapenemase-producing Enterobacterales outbreak: Another dark side of COVID-19.

Carbapenemase-producing Enterobacterales outbreak: Another dark side of COVID-19.
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产生甲状腺素酶的肠杆菌暴发:Covid-19的另一个阴暗面。

DOI:
10.1016/j.ajic.2020.09.015
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发表时间:
2020-12
影响因子:
4.9
通讯作者:
SARS-CoV-2 Hospital Foch study group
SARS-CoV-2 Hospital Foch study group
中科院分区:
医学3区
文献类型:
--
作者:
Farfour E;Lecuru M;Dortet L;Le Guen M;Cerf C;Karnycheff F;Bonnin RA;Vasse M;Lesprit P;SARS-CoV-2 Hospital Foch study group

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在专门为COVID-19患者服务的医院部门,感染预防和控制措施得到升级。因此,认为不太可能发生其他微生物的交叉传播。然而,我们报告了一次产NDM-5大肠杆菌的爆发。在一个专门收治COVID-19患者的12张病床的ICU中,此次疫情涉及6名患者,其中5名为无症状携带者,1名为感染者。一些发现可能导致交叉传播,包括科室的多卧室配置、标准和接触预防措施的不完全依从性、疾病负担导致的过度劳累、缺乏ICU患者护理人员培训以及手套滥用。此外,由于认为采取了感染预防和控制措施,因此未对接触患者进行eXDR携带筛查。应用严格的标准和接触预防措施,并在必要时对接触患者进行筛查,必须成为COVID-19病房的规则。
In the hospital department dedicated to COVID-19-patient, infection prevention and control measures were upgraded. Therefore, the cross-transmission of other micro-organisms was thought unlikely to occur. However, we report an outbreak of NDM-5-producing Escherichia. coli in a 12-beds ICU dedicated to COVID-19 patients. This outbreak involved 6 patients of which 5 were asymptomatic carriers and 1 was infected. Several findings might have contributed to cross-transmission including the multiple-bedroom configuration of the department, uncomplete compliance for standard and contact precautions, overwork due to the burden of the disease, lack of training of staff for the care of ICU-patients, and misuse of gloves. Furthermore, as infection prevention and control measures were thought to be applied, contact patients were not screened for eXDR carriage. Applying rigorously standard and contact precautions and performing screening in contact patients when indicated must be the rules in COVID-19 wards.
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