Asymmetric Direct Vinylogous Aldol Reaction of Furanone Derivatives Catalyzed by an Axially Chiral Guanidine Base
Asymmetric Direct Vinylogous Aldol Reaction of Furanone Derivatives Catalyzed by an Axially Chiral Guanidine Base
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DOI：
10.1002/anie.200906647
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发表时间：
2010-01-01
影响因子：
16.6
通讯作者：
Terada, Masahiro
中科院分区：
文献类型：
--
作者：
Ube, Hitoshi;Shimada, Naoki;Terada, Masahiro
与2-三甲基硅氧基呋喃的高对映选择性Aldol反应：第一个催化不对称自诱导Aldol反应作者希望感谢JC Jullian在NMR实验中的帮助，Dr. Franck教授激发了讨论，R. Hocquemiller对这项研究的持续兴趣。感谢MJ Vega Capela对十七醛的实验。L.塔奇和B。Mbeninack被公认用于制备（R，R）-2异构体。
Highly Enantioselective Aldol Reaction with 2-Trimethylsilyloxyfuran: The First Catalytic Asymmetric Autoinductive Aldol Reaction The authors wish to thank JC Jullian for his help in NMR experiments, Dr. X. Franck for stimulating discussions, and Prof. R. Hocquemiller for his continuous interest in this study. Thanks are due to MJ Vega Capela for the experiments with heptadecanal. L. Tache and B. Mbeninack are acknowledged for the preparation of the (R, R)-2 isomer.