Mean phase coherence as a measure for phase synchronization and its application to the EEG of epilepsy patients
Mean phase coherence as a measure for phase synchronization and its application to the EEG of epilepsy patients
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DOI:
10.1016/s0167-2789(00)00087-7
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发表时间:
2000-10-01
期刊:
影响因子:
4
通讯作者:
Elger, CE
中科院分区:
文献类型:
--
作者:
Mormann, F;Lehnertz, K;Elger, CE
We apply the concept of phase synchronization of chaotic and/or noisy systems and the statistical distribution of the relative instantaneous phases to electroencephalograms (EEGs) recorded from patients with temporal lobe epilepsy. Using the mean phase coherence as a statistical measure for phase synchronization, we observe characteristic spatial and temporal shifts in synchronization that appear to be strongly related to pathological activity. In particular, we observe distinct differences in the degree of synchronization between recordings from seizure-free intervals and those before an impending seizure, indicating an altered state of brain dynamics prior to seizure activity. (C) 2000 Elsevier Science B.V. All rights reserved.