Protein-Losing Enteropathy in a Case of Nodal Follicular Lymphoma without a Gastrointestinal Mucosal Lesion
Protein-Losing Enteropathy in a Case of Nodal Follicular Lymphoma without a Gastrointestinal Mucosal Lesion
复制标题
DOI：
10.2169/internalmedicine.47.1189
复制
发表时间：
2008-01-01
影响因子：
1.2
通讯作者：
Taniwaki, Masafumi
中科院分区：
文献类型：
--
作者：
Kaneko, Hiroto;Yamashita, Mihoko;Taniwaki, Masafumi
蛋白丢失性肠病（PLE）的特征是胃肠道血清蛋白丢失。它通常是由肿瘤、溃疡或长期淋巴管扩张引起的分泌过多引起的。然而，我们报道了一位患有腹膜淋巴结滤泡性淋巴瘤的 47 岁男性，但他却患上了 PLE，但没有患上这些疾病。内镜下可见十二指肠球部粘膜渗出白色液体，导致蛋白质持续流失。化疗有效，PLE 迅速减少。结节性淋巴瘤病变被认为会扰乱淋巴液流动并将其反流至十二指肠粘膜。据我们所知，这是第二例淋巴瘤患者出现无胃肠道粘膜病变的 PLE 的报告。
Protein-losing enteropathy (PLE) is characterized by gastrointestinal loss of serum protein. It is usually caused by hypersecretion from a tumor, ulcer, or long standing lymphangiectasia. However, we report a 47-year-old man of peritoneal nodal follicular lymphoma who developed PLE with none of them. Oozing of whitish fluid from duodenal bulbar mucosa was endoscopically seen, resulting in continuous loss of protein. Chemotherapy was effective and PLE was rapidly diminished. Nodal lymphoma lesion was considered to disturb lymphatic flow and to regurgitate it to duodenal mucosa. To our knowledge, this is the second report of a lymphoma patient presenting PLE without a gastrointestinal mucosal lesion.