The reaction of embryonic cells to solid structures
The reaction of embryonic cells to solid structures
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DOI：
10.1002/jez.1400170403
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发表时间：
1914-11-01
影响因子：
--
通讯作者：
Harrison, RG
中科院分区：
文献类型：
--
作者：
Harrison, RG
人们普遍认为，细胞和细胞团的运动是形态发生中的一个重要因素。后生动物发育过程中最明显的运动是细胞聚集体的运动，但这些运动往往因与生长或质量增加有关而变得复杂。另一方面，单细胞的运动，只涉及很小程度的生长，不那么复杂，同时，用我们现有的组织培养方法，很容易进行观察和实验。这种运动的机制是细胞原生质的流动，个体发育的结果取决于原生质本身的物理性质和作用于它的刺激。在他的"Reizphysiologie."甚至在此之前，勒布就已经考虑到了细胞的向性，并表明鱼胚胎中某些色素细胞的排列依赖于循环血液中发出的刺激。后来，Driesch也提出了这个问题，并发现了一个
It is generally recognized that the movement of cells and cell masses is an essential factor in morphogenesis.‘The most obvious movements concerned in the development of the Metazoa are those of cell aggregates, but these are often complicated by their association with growth or increase in mass. On the other hand, the movements of single cells, involving growth only to a very slight extent, are less complex and, at the same time, with our present methods of tissue culture, are readily amenable to observation and experiment. The mechanism of this movement is the streaming of the cell protoplasm, and the ontogenetic results depend upon the physical properties of the protoplasm itself and the stimuli which act upon it. The importance of such factors in development was fully recognized twenty years ago by ROUX~ in his experimental study of the behavior of isolated cells of the frog’s blastula, and by Herbst? in his ‘Reizphysiologie.’Even before this Loeb4 had considered the tropisms of cells, and had shown that the arrangement assumed by certain chromatophores in the fish embryo is dependent upon a stimulus emanating from the circulating blood. Somewhat later Driesch5 also took up the question and found a