Epidemiology of primary CNS neoplasms
Epidemiology of primary CNS neoplasms
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DOI：
10.1016/s0733-8619(05)70256-5
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发表时间：
1996-05-01
影响因子：
2.4
通讯作者：
PrestonMartin, S
中科院分区：
文献类型：
--
作者：
PrestonMartin, S
遗传综合征和电离辐射是原发性中枢神经系统肿瘤仅有的两种已知原因，各自仅占该疾病病例的百分之几。对于其他建议的风险因素，包括头部创伤，既往感染和杀虫剂等，研究结果是不确定的。脑肿瘤发病率的明显长期增加很可能主要归因于诊断的改善。神经胶质瘤和脑膜瘤的不同发生模式提示需要单独研究。未来的研究应致力于更精确地评估环境暴露，同时考虑个人的易感性。
Heritable syndromes and ionizing radiation, the only two established causes of primary CNS tumors, each account for only a few percent of cases of this disease. Findings are inconclusive for other suggested risk factors, including head trauma, prior infections, and pesticides, among others. The apparent secular increase in brain tumor rates is most likely predominantly attributable to improvements in diagnosis. The differing patterns of occurrence of gliomas and meningiomas suggest the need for separate study. Future studies should aim for more precise assessment of environmental exposure and simultaneous consideration of individual susceptibility.