EFFECT OF CRYOSURGERY ON PERIPHERAL-NERVES
EFFECT OF CRYOSURGERY ON PERIPHERAL-NERVES
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DOI：
10.1016/0022-4804(74)90036-5
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发表时间：
1974-01-01
影响因子：
2.2
通讯作者：
KETCHAM, AS
中科院分区：
文献类型：
--
作者：
BEAZLEY, RM;BAGLEY, DH;KETCHAM, AS
材料与方法用氟烷麻醉4只恒河猴，在无菌条件下暴露右侧面神经近端为颞面和颈面分叉。此时，利用Cooper-Linde CE-2冷冻手术装置和探针尖端为0.5 cm的PR-5探针，进行-40℃2分钟的冷冻损伤。完全解冻后，重复该病变。用贝克曼微热电偶[13]和霍尼韦尔Visicorder 1508B监测温度梯度。冷冻后，在冻疮近端神经刺激器（2 mA）的刺激不能激发面神经肌肉功能。定期观察神经功能恢复情况，用电影摄影记录。
MATERIALS AND METHODSFour Rhesus monkeys were anesthesized with Fluothane, and under aseptic conditions the right facial nerve was exposed proximal to the bifurcation into the temporo-and cervicofacial divisions. At this point, utilizing the Cooper-Linde CE-2 cryosurgery unit and the PR-5 probe with a 0.5 cm probe tip, a cryolesion measuring-40 C for 2 min was created. After complete thawing, this lesion was repeated. The temperature gradient was monitored with a Beckman’microthermocouple [13] and a Honeywell Visicorder 1508B. Following the freeze, stimulation by nerve stimulator (2 mA) t proximal to the cryolesion failed to elicit facial nerve muscle function. Periodic observations of nerve function return were made and recorded by cinephotography.