Retest reliability of plasma cholesterol and triglyceride. The Lipid Research Clinics Prevalence Study.
Retest reliability of plasma cholesterol and triglyceride. The Lipid Research Clinics Prevalence Study.
复制标题
重新测试血浆胆固醇和甘油三酯的可靠性。
DOI：
10.1093/oxfordjournals.aje.a113490
复制
发表时间：
1982
影响因子：
5
通讯作者：
Barrett-Connor,E
中科院分区：
文献类型：
--
作者：
JacobsJr,DR;Barrett-Connor,E
重测血浆胆固醇和甘油三酯的可靠性在诊断和研究计划中都很重要。在1972-1975年间脂类研究诊所患病率研究的第1次和第2次访问期间，胆固醇和甘油三酯的变异系数约为8%和25%。重测信度显示与其他研究因素的相关性很小或没有相关性。在没有明显解释的情况下，观察到50毫克/分升和偶尔100毫克/分升的明显胆固醇变化并不罕见。甘油三酯的明显随机变化可能高达数百毫克/分升。临床上重要的是，首次测量胆固醇和/或甘油三酯的高五分之一的人中，三分之二的人保持在这个级别，而在重新测试时，三分之一的人排在较低的位置，建议对这些血脂值进行多次观察，以用于临床和建立研究基线。
Retest reliability for plasma cholesterol and triglyceride is important diagnostically and In the planning of studies. Coefficients of variation of about 8% for cholesterol and 25% for triglyceride are reported here during Visits 1 and 2 of the Lipid Research Clinics Prevalence Study in 1972–1975. Retest reliability showed little or no dependence on other factors studied. It would not be unusual to observe apparent cholesterol changes of 50 mg/dl and occasionally 100 mg/dl with no obvious explanation. Apparent random triglyceride changes may be as high as several hundred mg/dl. It is of clinical importance that two thirds of persons In the upper quintile of cholesterol and/or triglyceride at first measurement remain In this rank and one third rank lower on retest Multiple observations of these lipid values are recommended both for clinical use and for establishment of study baselines.