RETRACTED: Effect of marijuana use on cardiovascular and cerebrovascular mortality: A study using the National Health and Nutrition Examination Survey linked mortality file
RETRACTED: Effect of marijuana use on cardiovascular and cerebrovascular mortality: A study using the National Health and Nutrition Examination Survey linked mortality file
复制标题
撤回：使用大麻对心脑血管死亡率的影响：一项使用国家健康和营养检查调查相关死亡率文件的研究
DOI：
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发表时间：
2017
影响因子：
8.3
通讯作者：
I. Okosun
中科院分区：
文献类型：
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作者：
Barbara A. Yankey;R. Rothenberg;S. Strasser;Kim Ramsey;I. Okosun
背景报告将大麻的使用与心血管紧急情况联系起来。将大麻使用与心血管死亡率相关的研究很少。大麻使用合法化的最新进展强调了了解大麻使用与心血管死亡之间关系的重要性；主要排名死亡率。休闲大麻主要用于吸食；我们假设，像吸烟一样，吸食大麻也会增加心血管死亡率。设计 本研究的设计基于死亡率随访。方法 我们将 20 岁及以上在 2005 年美国国家健康和营养检查调查期间回答大麻使用问题的参与者与国家卫生统计中心、疾病控制和预防中心 2011 年公共使用关联死亡率文件中的数据联系起来。仅包括符合死亡率随访资格的参与者。我们进行了 Cox 比例风险回归分析，以估计因使用大麻导致的高血压、心脏病和脑血管死亡率的风险比。我们控制了吸烟和其他相关变量。结果 1213 名符合条件的参与者中，72.5% 被认为还活着。总随访时间为19,569人年。与非大麻使用者相比，大麻使用者因高血压死亡的调整后风险比为 3.42（95% 置信区间：1.20–9.79），每年吸食大麻的风险比为 1.04（95% 置信区间：1.00–1.07）。结论 根据我们的结果，吸食大麻可能会增加高血压死亡的风险。吸食大麻时间的增加与高血压死亡风险的增加有关。娱乐性大麻的使用可能会对心血管产生不良影响，需要进一步研究。
Background Reports associate marijuana use with cardiovascular emergencies. Studies relating marijuana use to cardiovascular mortality are scarce. Recent advance towards marijuana use legalization emphasizes the importance of understanding relationships between marijuana use and cardiovascular deaths; the primary ranked mortality. Recreational marijuana is primarily smoked; we hypothesize that like cigarette smoking, marijuana use will be associated with increased cardiovascular mortalities. Design The design of this study was based on a mortality follow-up. Method We linked participants aged 20 years and above, who responded to questions on marijuana use during the 2005 US National Health and Nutrition Examination Survey to data from the 2011 public-use linked mortality file of the National Center for Health Statistics, Centers for Disease Control and Prevention. Only participants eligible for mortality follow-up were included. We conducted Cox proportional hazards regression analyses to estimate hazard ratios for hypertension, heart disease, and cerebrovascular mortality due to marijuana use. We controlled for cigarette smoking and other relevant variables. Results Of the 1213 eligible participants 72.5% were presumed to be alive. The total follow-up time was 19,569 person-years. Adjusted hazard ratios for death from hypertension among marijuana users compared to non-marijuana users was 3.42 (95% confidence interval: 1.20–9.79) and for each year of marijuana use was 1.04 (95% confidence interval: 1.00–1.07). Conclusion From our results, marijuana use may increase the risk for hypertension mortality. Increased duration of marijuana use is associated with increased risk of death from hypertension. Recreational marijuana use potentially has cardiovascular adverse effects which needs further investigation.
影响因子：
24
作者：
Sidney, Stephen;Quesenberry, Charles P., Jr.;Rana, Jamal S.
通讯作者：
Rana, Jamal S.
影响因子：
158.5
作者：
Stampfer, MJ;Hu, FB;Willett, WC
通讯作者：
Willett, WC