Risk for Depressive Symptoms among Hospitalized Women in High-Risk Pregnancy Units during the COVID-19 Pandemic
Risk for Depressive Symptoms among Hospitalized Women in High-Risk Pregnancy Units during the COVID-19 Pandemic
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DOI：
10.3390/jcm9082449
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发表时间：
2020-08-01
影响因子：
3.9
通讯作者：
Pariente, Gali
中科院分区：
文献类型：
--
作者：
Sade, Shanny;Sheiner, Eyal;Pariente, Gali
目的：在以往灾后进行的流行病学研究中，发现受影响人群中精神障碍，特别是抑郁症的发病率较高。本研究的目的是评估在“2019冠状病毒病”（COVID-19）大流行期间住院的孕妇与在COVID-19大流行之前住院的妇女的抑郁风险。研究设计：在索罗卡大学医学中心（SUMC）高危妊娠病房住院的妇女中进行了一项横断面研究。所有参与的女性均完成了爱丁堡产后抑郁量表（EPDS），并将在COVID-19严格隔离期间（2020年3月19日至2020年5月26日）住院的女性与COVID-19大流行前住院的女性的结果进行了比较。构建多变量逻辑回归模型以控制潜在混杂因素。结果如下：在COVID-19严格隔离期间住院的女性（n= 84）与COVID-19大流行前住院的女性相比，EPDS评分较高（>10）的风险相当（n= 279; 25.0% vs. 29.0%，p = 0.498）。这些结果在多变量logistic回归模型中保持相似，同时控制了母亲的年龄、种族和已知的情绪障碍（调整后的比值比（OR）1.0，95%CI 0.52- 1.93，p = 0.985）。结论：与COVID-19大流行前住院的女性相比，在COVID-19严格隔离期间在高危妊娠病房住院的女性患抑郁症的风险并没有增加。
Objective: Higher rates of mental disorders, specifically depression, were found among affected people in previous epidemiological studies taken after disasters. The aim of the current study was to assess risk for depression among pregnant women hospitalized during the "coronavirus disease 2019" (COVID-19) pandemic, as compared to women hospitalized before the COVID-19 pandemic. Study design: A cross-sectional study was performed among women hospitalized in the high-risk pregnancy units of the Soroka University Medical Center (SUMC). All participating women completed the Edinburgh Postnatal Depression Scale (EPDS), and the results were compared between women hospitalized during the COVID-19 strict isolation period (19 March 2020 and 26 May 2020) and women hospitalized before the COVID-19 pandemic. Multivariable logistic regression models were constructed to control for potential confounders. Results: Women hospitalized during the COVID-19 strict isolation period (n= 84) had a comparable risk of having a high (>10) EPDS score as compared to women hospitalized before the COVID-19 pandemic (n= 279; 25.0% vs. 29.0%,p= 0.498). These results remained similar in the multivariable logistic regression model, while controlling for maternal age, ethnicity and known mood disorder (adjusted odds ratio (OR) 1.0, 95% CI 0.52-1.93,p= 0.985). Conclusion: Women hospitalized at the high-risk pregnancy unit during the COVID-19 strict isolation period were not at increased risk for depression, as compared to women hospitalized before the COVID-19 pandemic.