GENDER DIFFERENCES IN CORRELATIONS OF CEREBRAL GLUCOSE METABOLIC RATES IN YOUNG NORMAL ADULTS
GENDER DIFFERENCES IN CORRELATIONS OF CEREBRAL GLUCOSE METABOLIC RATES IN YOUNG NORMAL ADULTS
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DOI：
10.1016/0006-8993(92)90817-s
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发表时间：
1992-03-06
期刊：
影响因子：
2.9
通讯作者：
HORWITZ, B
中科院分区：
文献类型：
--
作者：
AZARI, NP;RAPOPORT, SI;HORWITZ, B
在使用[F-18]2-fluoro-2-deoxy-D-glucose的“静息”状态（眼睛被遮住，耳朵被塞住）的健康受试者中，通过正电子发射断层扫描获得的标准化局部脑代谢数据的相关性分析表明，功能关联模式存在性别差异。 15名女性和18名男性（< 40岁）使用Scanditronix PC 1024 - 7 B断层扫描仪进行扫描。 大脑被划分为65个感兴趣区域（ROI）。 男性和女性在整体或区域代谢率或代谢左右不对称方面没有差异。 虽然男性和女性之间显著相关的总数没有差异，但模式不同：女性相关性r（F）比男性相关性r（M）更积极，而r（M）> r（F）;大多数r（F）> r（M）的情况涉及左额叶和感觉运动ROI，而大多数r（M）> r（F）的情况涉及右感觉运动和枕叶ROI。 研究结果表明，性别差异的功能性新皮层的互动模式在“休息”状态。
Correlational analysis of normalized regional cerebral metabolic data obtained by positron emission tomography, in healthy subjects in the 'resting' state (eyes covered, ears plugged) using [F-18]2-fluoro-2-deoxy-D-glucose, demonstrated gender differences in patterns of functional associations. Fifteen women and 18 men (< 40 yr) were scanned with a Scanditronix PC1024-7B tomograph. The brain was divided into 65 regions of interest (ROIs). There were no differences between men and women in global or regional metabolic rates, or in metabolic right-left asymmetries. Although the total number of significant correlations did not differ between men and women, patterns differed: female correlations r(F) were more positive than male correlations r(M) more often than r(M) > r(F); and most r(F) > r(M) cases involved left frontal and sensorimotor ROIs, whereas most r(M) > r(F) cases involved right sensorimotor and occipital ROIs. The findings demonstrate gender differences in the pattern of functional neocortical interactions at the 'resting' state.