Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing
Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing
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DOI：
10.1111/ics.12237
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发表时间：
2015-12-01
影响因子：
2.3
通讯作者：
Matts, P. J.
中科院分区：
文献类型：
--
作者：
Berardesca, E.;Ardigo, M.;Matts, P. J.
SynopsisObjectives探讨局部应用的金丝丝胶（GSS）复杂的生物物理参数相关的皮肤ageing.MethodsA范围内的非侵入性生物工程方法的影响部署在一个为期8周的随机，双盲，车辆对照，裂面研究40名女性受试者年龄在40-70。测量的终点包括皮肤状况、角质层（SC）水合作用、SC屏障功能、弹性和表面形貌的专家等级。
SynopsisObjectiveTo investigate the effects of topical application of a Gold Silk Sericin (GSS) complex on biophysical parameters related to skin ageing.MethodsA range of non-invasive bioengineering methods were deployed in an 8-week randomized, double-blinded, vehicle-controlled, split-face study among 40 female subjects aged 40-70. Endpoints measured included expert grades of skin condition, stratum corneum (SC) hydration, SC barrier function, elasticity and surface topography.ResultsThe GSS complex produced significant single-variable (P