Influenza A myocarditis developing in an adult liver transplant recipient despite vaccination: A case report and review of the literature
Influenza A myocarditis developing in an adult liver transplant recipient despite vaccination: A case report and review of the literature
复制标题
DOI：
10.1097/00007890-200008150-00026
复制
发表时间：
2000-08-15
期刊：
影响因子：
6.2
通讯作者：
Kusne, S
中科院分区：
文献类型：
--
作者：
Vilchez, RA;Fung, JJ;Kusne, S
接受慢性免疫抑制剂的实体器官移植受者尽管接种了疫苗，但感染流感病毒的风险仍会增加。心肌炎是一种已知但罕见的流感感染并发症。我们提出了第一个成年肝移植受者谁接受预防性疫苗接种，但发展为甲型流感心肌炎。这可能发生在实体器官移植受者中，因为他们对蛋白质疫苗的反应降低，这可能使他们容易受到感染。需要进行研究以评估在流感季节对实体器官移植受者进行抗病毒药物预防是否是针对这一高危人群的流感的有效预防性治疗。
Solid organ transplant recipients receiving chronic immunosuppressive agents are at increased risk to acquire influenza virus despite vaccination. Myocarditis is a known but rare complication of influenza infection. We present the first adult liver transplant recipient who received prophylactic vaccination but developed influenza A myocarditis. This may occur in solid organ transplant recipients, because they have reduced response to protein vaccines, which may leave them vulnerable to infections. Studies are needed to evaluate if antiviral chemoprophylaxis in solid organ transplant recipients during influenza season would be an effective preventive therapy against influenza in this high-risk population.