Characterization of cellular solids in Ti6Al4V for orthopaedic implant applications: Trabecular titanium
Characterization of cellular solids in Ti6Al4V for orthopaedic implant applications: Trabecular titanium
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DOI：
10.1016/j.jmbbm.2010.02.001
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发表时间：
2010-07-01
影响因子：
3.9
通讯作者：
Fearizzi, L.
中科院分区：
文献类型：
--
作者：
Marin, E.;Fusi, S.;Fearizzi, L.
EBM（电子束熔化）技术可以成功地用于在金属生物材料中获得细胞固体，其可以大大增加关节假体中的骨结合，同时保持良好的机械性能。被研究的结构，称为骨小梁钛，通常不能通过传统的机械加工获得。本项目生产并研究了两种样品：（A）具有较小的单电池面积，（B）具有较大的单电池面积。他们已经完全的特点，并与类似的文献中的结果进行比较有关的Ti6 Al 4V EBM结构。使用不同的方法评价相对密度，通过扫描电子显微镜图像计算开孔的平均直径;使用能量色散X射线光谱法评价组成;使用化学蚀刻研究微观结构（α-β），并且使用UMTS研究机械性能。平均孔隙率值与松质骨相当（A为63%，B为72%）。单一孔隙度的平均直径（A为650 μ m，B为1400 μ m）与文献中的骨整合数据一致，特别是对于样本A。维氏显微硬度测试和化学腐蚀测试表明，薄膜组织细小、均匀、分布均匀。力学试验证明，样品（A）比样品（B）更有抵抗力，但样品（B）显示出几乎等于松质骨的值的弹性模量。本研究的结果表明，这两种Ti6 Al 4V多孔固体可用于生物医学应用，以促进骨整合，表明它们可能成功地用于假体植入物。其他植入物结果将在不久的将来发表。(C)2010爱思唯尔有限公司保留所有权利。
EBM (Electron Beam Melting) technology can be used successfully to obtain cellular solids in metallic biomaterials that can greatly increase osseointegration in arthroprothesis and at the same time maintain good mechanical properties. The investigated structures, called Trabecular Titanium, usually cannot be obtained by traditional machining. Two samples: (A) with a smaller single cell area and, (B) with a bigger single cell area, were produced and studied in this project. They have been completely characterized and compared with the results in similar literature pertinent to Ti6Al4V EBM structures. Relative density was evaluated using different methods, the mean diameter of the open porosities was calculated by Scanning Electron Microscope images; the composition was evaluated using Energy-Dispersive X-Ray Spectroscopy; the microstructure (alpha-beta) was investigated using chemical etching and, the mechanical proprieties were investigated using UMTS. The mean porosity values resulted comparable with spongy bone (63% for A and 72% for B). The mean diameter of the single porosity (650 mu m for A and 1400 mu m for B) resulted compatible with the osseointegration data from the literature, in particular for sample A. The Vickers micro-hardness tests and the chemical etching demonstrated that the structure is fine, uniform and well distributed. The mechanical test proved that sample (A) was more resistant than sample (B), but sample (B) showed an elastic modulus almost equal to the value of spongy bone. The results of this study suggest that the two Ti6Al4V cellular solids can be used in biomedical applications to promote osseointegration demonstrating that they maybe successfully used in prosthetic implants. Additional implant results will be published in the near future. (C) 2010 Elsevier Ltd. All rights reserved.