PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1.
PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1.
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PET 引导下针导航活检有助于诊断 1 型神经纤维瘤病中的血管肉瘤。
DOI：
10.1002/pbc.24668
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发表时间：
2013
影响因子：
3.2
通讯作者：
Venkatesan,AradhanaM
中科院分区：
文献类型：
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作者：
Koethe,Yilun;Widemann,BrigitteC;Hajjar,Fouad;Wood,BradfordJ;Venkatesan,AradhanaM
在1型神经纤维瘤病(NF1)患者中，恶性变性通常发生于先前存在的丛状神经纤维瘤。由于CT不能区分同一肿瘤内的良性和恶性区域，用于诊断目的的图像引导活检对这些患者来说在技术上可能是具有挑战性的。多模式导航(PET、CT和超声)图像融合有助于成功活检和诊断1例NF1患者因盆腔神经纤维瘤引起的血管肉瘤。在此病例中成功地进行了靶向辅助治疗选择。这一新的导航技术可能有助于诊断NF1患者的恶性肿瘤，否则将非常困难。儿科血癌2013；60：E166-E169。©2013 Wiley期刊，Inc.
Malignant degeneration frequently arises from preexisting plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). Image guided biopsy for diagnostic purposes, such as with CT guidance, can be technically challenging in these patients, as CT cannot distinguish malignant from benign areas within the same tumor. Navigation with multi‐modality (PET, CT, and ultrasound) image fusion facilitated the successful biopsy and diagnosis of angiosarcoma arising from a pelvic neurofibroma in a patient with NF1. Successful targeting assisted treatment selection in this case. This novel navigation technique may facilitate the otherwise difficult diagnosis of malignancy in patients with NF1. Pediatr Blood Cancer 2013;60:E166–E169. © 2013 Wiley Periodicals, Inc.