Thalamic paraventricular nucleus neurons collateralize to innervate the prefrontal cortex and nucleus accumbens

Thalamic paraventricular nucleus neurons collateralize to innervate the prefrontal cortex and nucleus accumbens
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DOI:
10.1016/s0006-8993(97)01373-5
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发表时间:
1998-03-23
期刊:
影响因子:
2.9
通讯作者:
Deutch, AY
Deutch, AY
中科院分区:
医学3区
文献类型:
--
作者:
Bubser, M;Deutch, AY

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前额叶皮质和伏隔核是丘脑内侧传入的主要接受者,主要包括丘脑室旁核的投射。目前尚不清楚室旁神经元是否可以侧支支配前额叶皮质和伏隔核。我们使用双重逆行追踪方法来检查这个问题。少数脑室旁神经元支配前额叶皮质和伏隔内侧核。这些数据提示,丘脑室旁核可能协同影响前额叶皮质和腹侧纹状体的活动。(C)1998年爱思唯尔科学公司。
The prefrontal cortex and nucleus accumbens are primary recipients of medial thalamic inputs, prominently including projections from the thalamic paraventricular nucleus. It is not known if paraventricular neurons collateralize to innervate both the prefrontal cortex and nucleus accumbens. We used dual retrograde tract tracing methods to examine this question. A small population of paraventricular neurons was found to innervate the prefrontal cortex and medial nucleus accumbens. These data suggest that the thalamic paraventricular nucleus may coordinately influence activity in the prefrontal cortex and Ventral striatum. (C) 1998 Elsevier Science B.V.