OLIGODEOXYNUCLEOTIDES EMBODYING THE AMBIGUOUS BASE-Z, 5-AMINO-IMIDAZOLE-4-CARBOXAMIDE

OLIGODEOXYNUCLEOTIDES EMBODYING THE AMBIGUOUS BASE-Z, 5-AMINO-IMIDAZOLE-4-CARBOXAMIDE
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DOI：
10.1080/15257779508010683
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发表时间：
1995-01-01
期刊：
NUCLEOSIDES & NUCLEOTIDES
影响因子：
--
通讯作者：
DUGUE, L
DUGUE, L
中科院分区：
其他
文献类型：
--
作者：
POCHET, S;DUGUE, L

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使用磷酸三酯方法在溶液中合成含有5-氨基-1-（2-脱氧-β-D-呋喃核糖基）咪唑-4-甲酰胺（dZ）的短寡聚物。典型的碱使用的是醛酰基。对于Z残基的环外氨基官能团，引入了可氢解的苄氧羰基
Short oligomers containing 5-amino-1-(2-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide (dZ) were synthesized in solution using the phosphotriester methodology. Usual acyl groups were used for the canonical bases. For the exocyclic amino function of Z residue, the hydrogenolyzable benzyloxycarbonyl group was introduced