Multiple sclerosis following SARS-CoV-2 infection.
Multiple sclerosis following SARS-CoV-2 infection.
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DOI：
10.1016/j.msard.2020.102377
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发表时间：
2020-10-01
影响因子：
4
通讯作者：
Segura, T
中科院分区：
文献类型：
--
作者：
Palao, M;Fernandez-Diaz, E;Segura, T
SARS-CoV-2感染可产生神经系统特征。最常见的是头痛、嗅觉丧失和味觉障碍，但患者也可能发生其他中枢神经系统（CNS）损伤。我们介绍了一名受COVID-19影响的患者，他最初因视力下降而就诊。MRI显示右侧视神经炎症和CNS脱髓鞘病变。我们推测，SARS-CoV-2诱导的免疫机制，可以激活淋巴细胞和炎症反应，在疾病的临床发病中发挥作用。这种病原体可能与炎症/脱髓鞘疾病的触发或恶化有关。
SARS-CoV-2 infection can produce neurological features. The most common are headache, anosmia and dysgeusia but patients may also develop other central nervous system (CNS) injuries. We present a patient affected by Covid-19 who initially consulted for decreased visual acuity. The MRI showed inflammation in the right optic nerve and demyelinating lesions in the CNS. We speculate that an immune mechanism induced by SARS-CoV-2, which can activate lymphocytes and an inflammatory response, plays a role in the clinical onset of the disease. This pathogen may be associated with either the triggering or the exacerbation of inflammatory/demyelinating disease.