Cochlear aqueduct flow resistance depends on round window membrane position in guinea pigs
Cochlear aqueduct flow resistance depends on round window membrane position in guinea pigs
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DOI：
10.1007/s10162-004-5001-x
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发表时间：
2004-12-01
影响因子：
2.4
通讯作者：
Wit, HP
中科院分区：
文献类型：
--
作者：
Feijen, RA;Segenhout, JM;Wit, HP
本文测定了豚鼠耳蜗管内不同位置圆窗膜的流体流动阻力。这些不同的位置是通过对汽车中部的型腔施加不同的恒压来获得的。通过渡槽的流体流动是由叠加在这些恒定压力上的小压力阶跃引起的。结果表明，流体在渡槽中的流动阻力与圆窗位置有关，而与流向无关。这一结果可以用连接圆窗和渡槽入口的特殊纤维结构来解释。研究还发现，平衡内耳压力取决于中耳压力，这表明导水管没有将内耳与恒定压力的空腔连接起来。
The resistance for fluid flow of the cochlear aqueduct was measured in guinea pigs for different positions of the round window membrane. These different positions were obtained by applying different constant pressures to the middle car cavity. Fluid flow through the aqueduct was induced by small pressure steps superimposed on these constant pressures. It was found that the resistance for fluid flow through the aqueduct depended on the round window position but not on flow direction. The results can be explained by special fibrous structures that connect the round window with the entrance of the aqueduct. It was also found that the equilibrium inner ear pressure depends on middle ear pressure, indicating that the aqueduct does not connect the inner ear with a cavity with constant pressure.