Associations of unconventional natural gas development with depression symptoms and disordered sleep in Pennsylvania
Associations of unconventional natural gas development with depression symptoms and disordered sleep in Pennsylvania
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DOI：
10.1038/s41598-018-29747-2
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发表时间：
2018-07-27
影响因子：
4.6
通讯作者：
Schwartz, Brian S.
中科院分区：
文献类型：
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作者：
Casey, Joan A.;Wilcox, Holly C.;Schwartz, Brian S.
环境和社区因素可能影响抑郁症和睡眠问题的发展或过程。我们使用患者健康问卷-8和电子健康记录数据评估了非常规天然气开发（UNGD）与抑郁症症状和睡眠障碍诊断的关系，这些数据来自宾夕法尼亚州Geisinger成人初级保健患者。参与者在其住所接受了UNGD的回顾性指标（非常低、低、中、高），包括井开发的日期和持续时间、从患者家到井的距离以及井的特征。分析包括4,762名参与者，2014-2015年无（62%）、轻度（23%）、中度（10%）、中度或重度（5%）抑郁症状，2009-2015年期间诊断为3,868名睡眠障碍。我们观察到住得离更多更大的井更近和抑郁症状之间的联系，但在考虑抽样设计和参与的加权模型中没有观察到睡眠紊乱的诊断。在调整后的负二项模型中，高UNGD（相对于非常低）与抑郁症状相关（指数系数= 1.18,95%可信区间[CI]: 1.04-1.34）。在调整的多项逻辑模型中，高和低UNGD（相对于非常低）与抑郁症状相关（相对于无）。我们的研究结果表明，UNGD可能与宾夕法尼亚州的不良心理健康有关。
Environmental and community factors may influence the development or course of depression and sleep problems. We evaluated the association of unconventional natural gas development (UNGD) with depression symptoms and disordered sleep diagnoses using the Patient Health Questionnaire-8 and electronic health record data among Geisinger adult primary care patients in Pennsylvania. Participants received a retrospective metric for UNGD at their residence (very low, low, medium, and high) that incorporated dates and durations of well development, distance from patient homes to wells, and well characteristics. Analyses included 4,762 participants with no (62%), mild (23%), moderate (10%), and moderately severe or severe (5%) depression symptoms in 2014-2015 and 3,868 disordered sleep diagnoses between 2009-2015. We observed associations between living closer to more and bigger wells and depression symptoms, but not disordered sleep diagnoses in models weighted to account for sampling design and participation. High UNGD (vs. very low) was associated with depression symptoms in an adjusted negative binomial model (exponentiated coefficient = 1.18, 95% confidence interval [CI]: 1.04-1.34). High and low UNGD (vs. very low) were associated with depression symptoms (vs. none) in an adjusted multinomial logistic model. Our findings suggest that UNGD may be associated with adverse mental health in Pennsylvania.