Assessing the burden of disease in the United States using disability-adjusted life years

Assessing the burden of disease in the United States using disability-adjusted life years
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DOI:
10.1016/j.amepre.2005.02.009
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发表时间:
2005-06-01
影响因子:
5.5
通讯作者:
Marks, JS
Marks, JS
中科院分区:
医学2区
文献类型:
--
作者:
McKenna, MT;Michaud, CM;Marks, JS

文献摘要

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目标:许多国家已经实施了疾病负担研究,使用伤残调整生命年 (DALY) 来评估主要健康问题。 方法:我们应用世界银行和世界卫生组织 (WHO) 开发的方法,根据美国的特定数据来计算 DALY。我们将该分析的结果与世界卫生组织发布的世界发达和发展中地区的国际估计结果进行了比较。 结果:20世纪90年代中期,按照伤残调整生命年(DALY)衡量,美国过早死亡和残疾的主要来源是心血管疾病、乳腺癌和肺癌、抑郁症、骨关节炎、糖尿病以及酗酒。此外,与机动车有关的伤害和艾滋病毒流行对美国人口的健康状况造成了重大影响,特别是少数种族/族裔。后一人群中死亡和残疾的主要来源与发展中国家而不是发达国家的负担模式更相似。结论:本分析首次使用伤残调整生命年 (DALY) 对美国造成巨大健康负担的致命和非致命状况进行了详细、全面的估计。 (c) 2005 年美国预防医学杂志。
Objectives: Burden of disease studies have been implemented in many countries using the disability ad- usted life year (DALY) to assess major health problems.Methods: We applied methods developed by the World Bank and World Health Organization (WHO) to data specific to the United States to compute DALYs. We compared the results of this analysis to international estimates published by WHO for developed and developing regions of the world.Results: In the mid-1990s, the leading sources of premature death and disability in the United States, as measured by DALYs, were cardiovascular conditions, breast and lung cancers, depression, osteoarthritis, diabetes mellitus, and alcohol use and abuse. In addition, motor vehicle-related injuries and the HIV epidemic exacted a substantial toll on the health status of the U.S. population, particularly among racial/ethnic minorities. The major sources of death and disability in these latter populations were more similar to patterns of burden in developing rather than developed countries.Conclusions: This analysis provides the first detailed, comprehensive estimates using DALYs of the fatal and nonfatal conditions that exact large health burdens in the United States. (c) 2005 American journal of Preventive Medicine.